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Effect of Sert on Astrocytes and Microglial Cells of Cerebral in I/R Rats As illustrated in Fig

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NICE guidance (NG28) recommends that patients starting GLP-1 receptor agonists like Ozempic should have: Baseline assessment including HbA1c, renal function, and body weight Regular monitoring of glycaemic control and tolerability Review at 6 months to assess treatment response (defined as HbA1c reduction of at least 11 mmol/mol and weight loss of at least 3% of initial body weight) Ongoing assessment of cardiovascular risk factors Patients with pre-existing conditions require particular consideration

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Subsequent gene-expression analyses cited in the review identified GHK-Cu as modulating expression of approximately one-third of human genes, with a pattern consistent with reversal of age-related transcriptomic shifts