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NAC provides cysteine and glycine supplies another amino acid needed for glutathione synthesis

Pump the brakes with de-stressors like yoga, meditation, deep breathing, or tai chi, to help keep stress hormones and inflammation in check

GGT allows the degradation of GSH and the recycling of its constituent amino acids, such as glutamic acid and cysteine, to generate new GSH (so called -glutamyl cycle)

Since cysteine often becomes the rate-limiting amino acid, NAC supplementation can dramatically boost production

doi: 10.1007/s11864-022-01015-6, 130 WardR

Associations with polymorphisms in genes encoding UGT1A1, UGT1A6, UGT1A9, UGT2B15, and SULT1A1 were not detected in the same patient populations [100]