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(More information) Low folate status has been linked to increased cancer risk

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This systemic inflammation, akin to the processes described in schizophrenia, can traverse the blood-brain barrier or transmit via vagal afferents, subsequently activating microglia and exacerbating neuroinflammatory processes while impairing prefrontal cortex-mediated executive functions including decision-making and emotional regulation (270)

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5,10-methenyltetrahydrofolate synthetase deficiency