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Policy note: Research published in the Journal of Law and the Biosciences argues that allowing biosimilar applicants to challenge reference product patents earlier in the development timeline, specifically at Phase 3 initiation rather than 351(k) submission, would compress the 2.3-year post-expiry delay for settled and won cases to potentially under 1 year

On the other hand, glutathione depletion was shown to inhibit adipogenesis as the result of lowering cell proliferation during the initial mitotic clonal expansion of the adipocyte differentiation process [110]

doi:10.1016/j.mce.2014.12.021

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