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This is particularly valuable for addressing genes with defective proteins that are difficult to be targeted with conventional drugs, showing considerable potential in treating rare, chronic, infectious diseases and other metabolic disorders
Flucytosine, a synthetic fluorinated pyrimidine used to treat fungal respiratory tract infections, has also been shown to inhibit expression of the pyoverdine siderophore-biosynthesis gene in Pseudomonas aeruginosa , and subsequently suppress pathogenicity in a mouse model of pulmonary infection (Imperi et al., 2013)
doi: 10.1002/adma.202310174 118 DavisonJ
Enhanced metabolic support Vitamin B3 plays a key role in converting food into cellular energy (ATP)
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