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Introduction The skin is the largest organ in our body, acting as the first line of defense against external irritants and pathogens

Reproductive Toxicology 34: 357-363, 2012

Deficiency of Vitamin D is common in sickle cell disease due to dark skin pigmentation, limited sun exposure, increased catabolism and decreased nutrient and energy intake

Patients can present with the following signs & symptoms: CNS (areflexia, asthenia, ataxia, blurred vision, disorientation, dizziness, drowsiness, hyporeflexia, slurred speedh, somnolence, staggering, tiredness, coma) Cardiovascular (initial hypertension, followed by long-lasting hypotension , bradycardia , premature ventricular beats) the peripheral actions of xylazine cause an initial increase in blood pressure, followed by central effects that result in a long-lasting hypotensive effect, accompanied by bradycardia and reduced cardiac output (Hoffman et al, 2001)

10.1002/jmv.25801 44

The Targetable Nanoparticle BAF312@cRGD-CaP-NP Represses Tumor Growth and Angiogenesis by Downregulating the S1PR1/P-STAT3/VEGFA axis in Triple-Negative Breast Cancer