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Using the same site weekly accelerates lipohypertrophy and increases pain with each subsequent injection

Because of the significant risks associated with compounded tirzepatide, the FDA strongly recommends using an FDA-approved tirzepatide drug like Zepbound or Mounjaro when it is available

Baseline information on included trials can be found in Supplementary Table S3

Common adverse effects include nausea, diarrhea, vomiting, and constipation, which are typical for medications affecting gastrointestinal hormones

J Biol Chem 263(18):86218624 Reimann F, Gribble FM (2002) Glucose-sensing in glucagon-like peptide-1-secreting cells

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