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It remains unknown whether senescent neurons, or other cells with a similar gene expression profile, should be actively removed from its tissue or if it would be advantageous to simply target their detrimental SASP and ameliorate the likelihood of senescence, and associated inflammation, spreading

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In vitro studies have shown that genistein inhibits the proliferation of human keratinocyte HaCaT cells and reduces the expression of inflammatory cytokines induced by TNF-