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This correlated with rescue of muscle weight/body weight ratios in older mice in locomotory (gastrocnemius, quadriceps, triceps) and respiratory (diaphragm) muscles

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This activation enhances glutamate release from primary afferent terminals, resulting in increased normal and miniature excitatory postsynaptic currents, and elevates PKC activity, which mediates the phosphorylation of NMDARs (e.g., the GluN1 subunit at Ser896)

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