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While the impact of GLP-1 on health outcomes for diabetes and obesity has been revolutionary, payors are actively looking to mitigate projected health costs

Conversely, high BMI alone without metabolic dysfunction or cardiovascular risk may not automatically warrant GLP-1 therapy

Step 2: Introducing Semaglutide Semaglutide started as treatment for type 2 diabetes, but weight loss researchers soon found it was effectivevery effective

Since background BMI can be largely different between races, caution is needed when interpreting and applying the results, including combination use with SGLT2is and finerenone

A blood glucose level of 54 mg/dL or less was reported in 26% of patients receiving the 7 mg tablets, 30% of patients receiving the 14 mg tablets, and 32% with placebo