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In three of the studies, the sulfonylurea was used in monotherapy (7981), in one study the sulfonylurea was used in combination with metformin (82) and one study allowed sulfonylurea both as monotherapy and in combination with metformin (78)

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility

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Molecular Metabolism , 18, 3-14