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This latest study adds to a growing body of data on the positive cardiovascular effects of GLP-1-RAs beyond their initial indications for diabetes and weight management

Freezing reconstituted solution destroys peptide structure through ice crystal formation

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Pfizer reported that while the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron was in line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury that resolved after discontinuation of danuglipron

Effects of intrauterine extracellular vesicle microRNAs on embryonic gene expression in low-fertility cows

Participants who started at 1mg and escalated slowly over weeks experienced substantially fewer GI issues than those assigned directly to higher doses