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Many patients abandon the drug in a matter of months, due to cost, availability, and side effects

This work is also limited by the demographics of our participants, who were predominantly white, tended to be young, and had high income and educational attainment

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Negative evidence: A study in Indonesian individuals showed that supplementation with glutathione combined with vitamin C, alpha-lipoic acid, and zinc did not significantly lighten skin compared to placebo (Sitohang et al., J Clin Aesthet Dermatol, 2021) [63]