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333,334 However, in patients with T2DM, correcting hyperglycemia with insulin therapy has a limited impact on DPN

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Promoting AMP-Activated Protein Kinase (AMPK) Pathway: MOTS-c activates AMPK, often called the bodys master metabolic switch. Activating AMPK signals to your cells that energy is needed, which triggers the burning of fat for fuel, enhances glucose uptake, and promotes the creation of new mitochondria (a process called mitobiogenesis)

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