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Nrf2 plays an important role in regulating inflammatory factors, such as TNF- and IL-6, by modulating the nuclear factor kappa-B (NF-B) signalling pathway [108]

27 , 12221235.e1226 (2018)

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By signaling immune cells to reduce excessive inflammatory responses, it helps prevent chronic tissue damage

Metadynamics Well-tempered metadynamics simulation 39 was performed on Gly376 by GROMACS patched with PLUMED v2.2.3 22 , using as collective variable (CV) the backbone dihedral angle phi and psi

Mixture was left in dark for a further sixty minutes