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STEP2 and related trials in adults with type 2 diabetes and overweight/obesity demonstrated somewhat smaller absolute weight reductions (e.g., ~9.6% vs 3.4% at 68 weeks
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For some, semaglutide during menopause has been genuinely life-changing especially when hormonal changes make it even harder to lose weight
However, paradoxically, excessive Fe accumulation can trigger intracellular iron overload, promoting ferroptosis
