Effect of oxyntomodulin, glucagon, GLP-1, and combined glucagon +GLP-1 infusion on food intake, appetite, and resting energy expenditure
Similarly, tirzepatide (Zepbound) demonstrated up to 22.5% weight loss in a 72-week trial with the same approach
Weight loss at 48 weeks was clearly dose-dependent
But that also affects their water intake
Taking the Next Step with Rixa Health Our Medical Weightloss Approach for PCOS cuts through the noise and confusion with a clear, science-backed protocol: Initial Consultation and Assessment Your journey begins with a comprehensive evaluation: Detailed medical history focusing on your PCOS symptoms Review of previous treatments and their effectiveness Discussion of your specific goals beyond weight loss Explanation of how GLP-1 medications work specifically for your PCOS type Answering all your questions (no rushing through appointments) Your Personalized Treatment Plan Based on your assessment, we create a tailored plan that includes: The optimal GLP-1 medication and starting dose for your specific needs A PCOS-specific nutrition approach that works with the medication Supplement recommendations to address common PCOS deficiencies Activity guidance optimized for hormone balance Clear expectations and timeline for results Ongoing Support and Optimization Your progress is carefully monitored with: Regular check-ins to assess symptoms, side effects, and results Dose adjustments based on your response Lab work to track hormonal improvements, not just weight Modifications to your plan as needed to maximize results Educational resources to help you understand your body Ready to finally address the root cause of your PCOS rather than just managing symptoms
b Estimated using an ANCOVA based on data irrespectively of discontinuation of trial product or initiation of rescue medication adjusted for baseline value, background medication, renal status and region
