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Early studies of GLP-1s showed patients decreased their food consumption based on reaching satiety and made broader behavioral shifts as they adopted healthier lifestyles

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108,109 Members of the subfamily II of the SLC30 proteins (ZnT2, ZnT3, ZnT4, and ZnT8) play a major role in secretory tissues, with ZnT3 involved in neurotransmission, ZnT8 in insulin storage, ZnT4 in prostate secretion, and ZnT2 in lactation

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