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Role of gut microbiota in regulating satiety hormone secretions Gut microbiota affect inflammatory processes Another way in which gut microbiota can affect satiety is by affecting the inflammatory processes in the hypothalamus
PDX-1 is an essential transcription factor for all stages of pancreatic development and plays a key role in beta cell differentiation, proliferation, survival, maturation, and function [30]
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Reintroducing specific commensal species, such as Lactobacillus reuteri and Bacteroides thetaiotaomicron, into mice lacking gut microbiota lowers elevated GLP-1 levels and normalizes locomotor activity, thereby establishing a direct connection between microbial composition and GLP-1-related neuroendocrine effects
10.1089/ars.2016.6850 15 EitaA