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Chronic colitis induces meninges traffic of gut-derived T cells, unbalances M1 and M2 microglia/macrophage and increases ischemic brain injury in mice

Cell Metab (2006) 3:16775.10.1016/j.cmet.2006.02.004 185 ChuZLJonesRMHeHCarrollCGutierrezVLucmanAet alA role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release

Although previous ex vivo studies employing NCI-H716 cells (a human L cell line) [35] or human ileal and colonic tissues [14] were indicative of a direct effect of metformin in stimulating GLP-1 release, clinical evidence suggests that the augmentation of postprandial GLP-1 secretion by metformin is largely indirect

Keep your diet flexible so you can stay consistent, and use supplements where theyre needed

Elevate your head: Use a wedge pillow to elevate your upper torso by 30 degrees

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