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Common symptoms include: Nausea (affecting 1040% of patients) Vomiting Diarrhoea Constipation Abdominal discomfort or pain Reduced appetite These effects are usually mild to moderate and tend to diminish over several weeks as the body adjusts to the medicine

Additionally, protein post-translational glycosylation-mediated association between the levels of von Willebrand factor (vWF) and ABO blood groups has been established [52]

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Oxidative folding of interleukin-2 is impaired in flavin-deficient Jurkat cells, causing intracellular accumulation of interleukin-2 and increased expression of stress response genes

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