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A preclinical performed by Talib highlighted the promising role of combining a KD with melatonin in addressing chemotherapy resistance in breast cancer

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However, caution must be exercised to monitor for potential toxic reactions, including neurotoxicity and hematotoxicity, thus necessitating rigorous evaluation of such combinations

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Acute phase proteins have been shown to positively correlate with erythrocyte glutathione concentration in humans (Reference Trzeciak, Mohanty and Jacob65)