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The factors that lead to depletion of glutathione includes natural ageing process, or the external stressors that include chronic exposure to chemical toxins, cadmium exposure, alcohol use, smoking, pollution, strenuous aerobic activities, dietary factors, ultraviolet (UV) radiation exposure, tissue injury as from burns, ischemia, septic shock, surgery, drugs (such as acetaminophen and adriamycin)

Palmatine ameliorates cisplatin-induced acute kidney injury through regulating Akt and NF-B/MAPK pathways

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In conclusion, DV2 infection could reduce host intracellular GSH concentration and benefited from this process

[Isoform Cytoplasmic]: Cytoplasm