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Our progress in understanding the molecular mechanisms governing eryptosis allowed shedding light on signaling pathways mediating the development of morphological alterations associated with eryptosis
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For instance, it has been reported that hypothyroidism-induced dysfunction of the mitochondrial respiratory chain is associated with increased production of free radicals (59) Thus, excess TSH in hypothyroidism may modulate oxidative stress processes (60) by augmenting the accumulation of ROS that result from both increased generation of free radicals and diminished capacity of the antioxidative defense systems
Massi, F., Grey, M
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