molecular hydrogen nrf2 glutathione activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer: Cell Metabolism Nrf2 Regulates Basal Glutathione Production

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The existing body of literature underscores the challenges associated with GSH's poor bioavailability, attributed to its unfavorable biochemical and pharmacokinetic properties 10,16

173,174 In addition, arginine methylation also affects proteinprotein interactions involved in various cellular processes such as protein trafficking, signal transduction and transcriptional regulation