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Patients with severe systemic lupus erythematosus who are ineffective on immunosuppressants can combine bortezomib and steroids, which are well tolerated and effective in long-term use[73]

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Nanotechnology carriers, such as antioxidant-loaded liposomes or polymeric nanoparticles, further improve bioavailability and provide synergistic effects in alleviating oxidative stress and bolstering melanocyte survival (142)

[DOI] 199.Vaziri-harami R., Delkash P