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High-free androgen index is associated with increased risk of non-alcoholic fatty liver disease in women with polycystic ovary syndrome, independent of obesity and insulin resistance

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Other suggested mechanisms that might explain differences between obese and lean genotypes include thermogenesis [40], altered methylation patterns [41], intestinal microbiome alterations [42], and changes in energy expenditure [43]

-glucan: high-molecular-weight -glucan derived from oats (3 g/day) has been shown to increase the abundance of Bacteroides and Prevotella while decreasing pro-inflammatory Dorea species (121)

The textbooks describe a fairly recognisable profile: Mean age at diagnosis around 42 , with a wide range across all adult ages

While it reaches systemic circulation more efficiently, the lipid coating still releases some glutathione in the intestinal tract during digestion