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Im curious to see how much of this effect is driven by GLP-1s central dopaminergic modulation vs

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Losing muscle while losing fat can lead to aslower metabolism, making it harder to sustain results after treatment ends

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Important safety considerations include risk of pancreatitis (treatment should be discontinued if suspected), gallbladder disease, and potential worsening of diabetic retinopathy in patients with pre-existing retinopathy who experience rapid improvement in glucose control (particularly with semaglutide)

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