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( A ) Western blot analysis of sAC in bound and unbound fractions from pull-down experiments using streptavidin magnetic beads with biotinylated GLP-1(2836) and scrambled control incubated with mouse whole-heart lysates indicated no sAC binding to either peptide

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High-fiber diets may modestly increase endogenous GLP-1 secretion, though effects are minimal compared to medications

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