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Furthermore, ABCC5 overexpression increased SLC7A11 expression, decreased lipid peroxidation, and increased intracellular GSH levels, resulting in reduced ferroptosis (91)

2 Cholesterol sources Cholesterol in the body comes from two main sources: it is either synthesized de novo by the cells or obtained from dietary intake, especially from foods of animal origin

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Since they mimic natural biological processes, the body handles them well

However, these therapies often exhibit limited long-term efficacy, may cause severe adverse effects, and remain largely insufficient in preventing the progressive accumulation of irreversible disability driven by axonal and neuronal damage