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The role of increased fatty acid and glucose metabolism, mitochondrial dysfunction, and increased protein acetylation in the DKD pathology (2)

The efficacy of acetylcysteine decreases after the first 8 hours following an acute paracetamol overdose, with a corresponding stepwise increase in hepatotoxicity with increasing treatment delays between 8 and 16 hours

Toxicol Appl Pharmacol 1984;74:11624

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