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Cagrilintide is a synthetic analog of the endogenous hormone amylin and is classified as an amylin receptor agonist
The mechanism of action involves binding to both GIP and GLP-1 receptors, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, and promotes satiety through central nervous system pathways
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95, 48894897.10.1210/jc.2009-1730 97 FazeliP
