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A number of recent studies and meta-analyses have shed new light: A 2024 meta-analysis of 21 RCTs involving over 25,000 patients found that semaglutide was associated with a 30% reduction in AF occurrence compared to control medications (RR 0.70, 95% CI 0.520.95)

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And at 48 weeks, of those given 4mg, 92% of Retatrutide participants lost 5% or more, 75% of these people lost 10% or more, and 60% of them lost 15% or more

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TNF- = tumour necrosis factor alpha