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Specialized pro-resolving mediators in Neuroinflammation: overview of studies and perspectives of clinical applications

10.18632/aging.100968 37 ShareckM.RousseauM.-C.KoushikA.SiemiatyckiJ.ParentM.-E

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Initially, it was approved for the treatment of type 2 diabetes, where it proved highly effective in improving blood sugar control

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While previous studies identified the serotonin 5-HT 3 receptor in cells as a mediator of serotonin-induced insulin secretion (47, 62), here we demonstrate that serotonin receptor 3 antagonist (ondansetron) was not able to block serotonin-induced hypoglycemia