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Visceral fat reduction can significantly reduce disease risk and enhance long-term health, making it a primary focus in obesity treatment

4.2 Limitations This meta-analysis has several limitations

Despite the controversies about the expression of GLP-1R in vascular smooth muscle and endothelial cells, studies have shown that GLP-1RAs have anti-proliferative effects on these cells, and also reduced oxidative stress and increased the production of nitric oxide (NO) (137, 138)

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XULTOPHY [ZUL toh fye] pairs liraglutide with insulin degludec (Tresiba)

All patients with DKD and proteinuria should be on an ACE inhibitor or angiotensin receptor blockers (ARB) at the maximally tolerated dose