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5.4 Comparative therapeutic efficacy The translation of therapeutic agents from animal models to clinical trials faces significant barriers

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Coniferyl ferulate is a potent inhibitor of glutathione S-transferase ( GST ) ( IC = 0.3 M), which downregulates 50 P-gp expression, induces apoptosis in B-MD-C1 (ADR+/+) cells, and reverses multidrug resistance

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It is regarded as food for the brain and involved in energy production