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Published in the New England Journal of Medicine in 2022, the trial enrolled 2,539 adults without type 2 diabetes who had a BMI of 30 or higher, or 27 or higher with at least one weight-related comorbidity

Both help manage it effectively when used thoughtfully and combined with healthy lifestyle practices

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The GIP receptor agonism complements GLP-1 receptor activation by enhancing glucose-dependent insulin secretion, thereby improving glycemic control and weight loss more effectively than GLP-1RAs alone

dedicated kidney-outcome and heart-failure trials of GLP-1RAs in chronic kidney disease and obesity-related heart failure with preserved ejection fraction have further broadened their role

The solution should look like water