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A researcher must calculate total peptide content per unit volume across all three compounds

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In one study of perceptions of long-acting injections (LAIs) compared to pills, for example, the perceived advantage for LAI over pills and the belief about the better efficiency of LAI were the main factors that drove the preference for LAI

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In practice, optimal intranasal dosing is often established through a combination of in vivo pharmacokinetic studies, brain-to-plasma exposure ratios, and pharmacodynamic endpoints, rather than relying solely on systemic dose equivalence (Dhuria et al., 2010)