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Trends Cell Biol 20(2):102112 Koehler RC, Roman RJ, Harder DR (2009) Astrocytes and the regulation of cerebral blood flow

One such study found that GLP-1 elevates intracellular cAMP, subsequently activating protein kinase A (PKA), which in turn inhibits RhoA/ROCK signaling, resulting in the disassembly of glucotoxicity-induced stress fibers 6

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For healthy adults, moderate intermittent fasting is generally considered safe, and no reputable schedule recommends fasting more than a day at a time