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In the first cohort we compared GLP-1 RA users with SGLT-2 inhibitor users during the study period 2014-2022

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Highlights: GLP-1 receptor agonists were associated with a slightly higher relative risk of nonarteritic anterior ischemic optic neuropathy (NAION) , although the one-year absolute risk remained only 0.04% A nationwide Swedish cohort study followed more than 293,000 adults with type 2 diabetes who started GLP-1 receptor agonists or SGLT-2 inhibitors