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As NAc is also an important brain region associated with GLP-1-induced feeding suppression, further electrophysiological studies are necessary to explore the contribution of glutamatergic neurotransmission to endogenously released GLP-1-induced suppression of high-fat food intake in the VTA

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For instance, HIF-1 is implicated in the proliferation, migration, and invasion of FLS in RA patients, regulating angiogenesis and inflammatory responses (136), as well as joint erosion and bone degradation (137)