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As a result, the ECM transitions from a supportive scaffold to a pathological regulator of hepatic injury and fibrogenesis

OSR alleviates OA by activating GPX4/SLC7A11 to regulate ROS and oxidative stress, emerging as a promising OA therapeutic candidate, offering insights into redox-targeted interventions

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This mechanism has also been proposed for glucose/fructose-mediated GLP-1 secretion in-vitro and in the perfused rat small intestine [20, 31]

Chromatin immunoprecipitation (ChIP) ChIP assays were performed using a ChIP Assay Kit (Millipore, 17-295)

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