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An RCT in 36 patients with type 2 diabetes found that NAC (1,200 mg/day for 4 weeks) combined with a standard diabetes diet significantly reduced fasting glucose, HbA1c, and markers of oxidative stress compared to diet alone (Shahidi et al., J Diabetes Metab Disord, 2020) [56]

Signal transducer and activator of transcription 3 (STAT3) binds to DNA response elements in the promoters of ferroptosis-related genes (FTH1, SLC7A11, and GPX4) and regulates their expression

Glutathione is a powerful tripeptide produced naturally by our bodies, specifically within the liver

State boards of pharmacy provide primary oversight, but standards and enforcement vary by state

Afterward, the patient should begin maintenance treatment

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