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We propose that mitohormesis may be optimally activated by strategies that facilitate a balanced oscillation between challenging (but not excessive) stressor phases, which temporarily disrupt mitochondrial biology, and complete (but not excessive) recovery phases, which provide adequate time for mitochondria to repair and recalibrate prior to the next stressor (Table 1)

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Efficacy and site specificity of hydrogen abstraction from DNA 2-deoxyribose by carbonate radicals

10.1016/j.biopha.2019.109316 199 WangP.WangW.ShiQ.ZhaoL.MeiF.LiC.et al (2016)

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