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These results suggest that glial cells play a key role in the pathogenesis of PD, and in particular, the release of inflammatory cytokines in dopaminergic neurons may be one of the main mechanisms responsible for PD pathogenesis

We then tested whether other agents that specifically caused nucleotide imbalance (rather than the DNA-driven and RNA-driven effects of 5FU) have the same mechanism of action

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If you freeze a 5mL vial and thaw it six times over three months, you've introduced cumulative damage that refrigeration alone would have avoided