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Scenario A: Metabolic Rescue (High Risk, Suitable for Application) Target population: women with BMI 30 kg/m 2 plus marked IR or metabolic syndrome

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Some regulatory pathways, like Premarket Approval (PMA), can take far longer than 180 days, especially if there are deficiencies in the initial application

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Week 8-12 (Escalation check): Retest fasting glucose, lipase, ALT, AST

These drugs can help people control their type 2 diabetes or lose weight, but the drugs also have many potential side effects