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In humans, the DPP4 gene is located on chromosome 2 locus 2q24.3 and composed of 26 exons that encode a protein of 766 amino acids [29]

FDA approval for tirzepatide required Phase 3 randomised controlled trials demonstrating safety and efficacy in over 6,000 participants

These cells are effectively broken down and mobilized for removal

Foam-based topical delivery format has been examined in peptide absorption profiling and follicular penetration studies within non-clinical laboratory settings

Limitations Few studies evaluated newer medications (e.g., GLP-1 receptor agonists) with follow-up beyond 12 months

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