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Lastly, glimepiride, a third-generation sulfonylurea, was introduced in 1995 in the United States (Tan and Nelson, 1996)

In clinical settings, pegloticase and SEL-212 formulations, combined with immunomodulators (e.g., methotrexate/sirolimus), suppress anti-drug antibody formation to maintain uricase activity, achieving long-term uric acid control and tophus resolution

Table 1 Methods for detecting ferroptosis

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Role of oxidative stress and inflammation in insomnia sleep disorder and cardiovascular diseases: herbal antioxidants and anti-inflammatory coupled with insomnia detection using machine learning

Several lignans have shown neuroprotective properties in experimental models of PD