| Medication | Monthly Cost (2026) | Mechanism | Avg Weight Loss | |-----------|-------------------|-----------|-----------------| | Retatrutide (compounded) | $200650 | Triple agonist (GLP-1/GIP/glucagon) | 24% | | Wegovy (semaglutide) | $1,300+ | GLP-1 only | 15% | | Zepbound (tirzepatide) | $1,059+ | Dual agonist (GLP-1/GIP) | 21% | | Mounjaro (tirzepatide) | $1,023+ | Dual agonist (GLP-1/GIP) | 21% | | Ozempic (semaglutide) | $935+ | GLP-1 only | 12-14% | *Note: Compounded retatrutide prices reflect direct pharmacy costs with valid prescription
Female subjects reported more GI AEs in all groups compared with men (55.6 vs 48.5% for semaglutide and 37.7 vs 32.0% for placebo)
The formulation is supplied as a lyophilized powder in sterile, sealed vials at research-grade purity, designed for use in controlled laboratory settings investigating multi-pathway cellular and tissue responses
Participants typically receive: Weekly injections (either the drug or placebo) Regular medical check-ups Laboratory testing Dietary and lifestyle guidance Many trials last 4868 weeks, followed by additional observation periods
However, this would depend on their unique health profile
Feb 3, 2026 A peptide that kills fat cells
