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The focus of future research will be to determine if any of these discoveries are dependent on one another biochemically, what is the cross talk between the various aspects of redox regulation, and how, together, they contribute to parasitism

Shimada et al

Cell Metab 2022;34:1054-63.ArticlePubMedPMC 17

Because each sequence in the initial alignment has a length of 30 amino acids and each position can be mutated to one of 19 amino acids (20 if the position is gapped), this gives 570 single-step mutants in the first generation for each sequence in the training set, that is, 71,304 sequences, reducing to 69,639 sequences after removing duplicates

In silico-based experiments on mechanistic interactions between several intestinal permeation enhancers with a lipid bilayer model

While these features are essential for host protection, they pose significant challenges to oral drug delivery